Evaluation of Porcine Small Intestinal Submucosa in Achilles Tendon Repair
نویسندگان
چکیده
Background: Tendon defects remain a major concern in orthopedic surgery because of the limited availability of tendon autografts. Since the extracellular collagen-based matrix derived from porcine small intestinal submucosa (SIS) has been successfully used in repair of many tissues, such as abdominal wall, vessels and bladder, we hypothesized that SIS can be used to repair an experimentally induced Achilles tendon defect. Material and Methods: Seventeen New Zealand rabbits were submitted to Achilles tendon resection (1.5 cm length) in the right posterior limb and this defect was repaired with SIS. The left Achilles tendon (sham operated) was used as a control. Daily examination was performed for 30 days. On the day of sacrifice, Achilles tendon from both limbs was excised and signs of infection, dehiscence, incorporation and degree of adhesion were evaluated. Tensiometry, Ramos-vol5no1 3/19/05 11:39 AM Page 115
منابع مشابه
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